Restylane Kysse is a next-generation hyaluronic acid (HA) dermal filler formulated exclusively for the lips and perioral area. It is injected into the lips and the lines around the upper lip to temporarily increase fullness, refine lip shape and smooth vertical lip lines (perioral rhytids) in adults over 21 years old.
The filler uses Galderma’s XpresHAn™ technology, which creates a soft, flexible gel that integrates seamlessly into the lip tissue. This allows the lips to stay expressive and mobile—so they still look and feel like your own lips, just with better definition and volume.
Restylane Kysse also contains a small amount of lidocaine (0.3% w/v) to increase comfort during injection.
Compared to generic fillers used “off-label” in the lips, Restylane Kysse is specifically studied and approved for this area, with clinical data showing improvements in lip fullness, texture, colour and patient satisfaction that can last up to 1 year.
Restylane Kysse adds smooth, controlled volume to thin or deflated lips, enhancing body and shape without an overfilled or “stiff” appearance, thanks to its soft, flexible HA gel.
By precisely supporting the lip borders and cupid’s bow, Kysse refines lip contour, improves asymmetry and creates a more balanced, harmonious smile.
Clinical studies show that Restylane Kysse can improve the texture and surface smoothness of the lips, as well as subtly enhance natural lip colour, giving lips a fresher, more youthful look.
Beyond the lip body itself, Restylane Kysse can be placed in the fine vertical lines above the upper lip (perioral lines), helping soften “barcode” lines that can age the mouth area.
XpresHAn™ technology allows the filler to move naturally with your facial expressions, so lips stay soft and “kissable” while maintaining enhancement for up to 1 year in many patients.
Restylane Kysse contains stabilised hyaluronic acid, a sugar molecule naturally found in the skin that attracts and holds water—crosslinked to form a smooth, flexible gel. XpresHAn™ technology tailors the filler’s structure to move and stretch with dynamic areas like the lips.
Using fine needles or cannulas, the doctor injects small amounts of the gel into different parts of the lips (body, border, cupid’s bow) and, when needed, into lines above the upper lip. Placement and volume are customised to your anatomy and goals—whether subtle refinement or more noticeable plumpness.
Once placed, the HA gel immediately supports and gently expands the lip tissue, giving instant volume and contour. At the same time, its water-attracting properties help hydrate and smooth lip surfaces.
As swelling settles over the following days, the filler integrates with your own tissue. The lips remain soft and mobile, with results that can last up to 12 months, depending on individual metabolism, lifestyle and the amount of product used.
Restylane Kysse is ideal for patients seeking lip enhancement with a natural feel and movement, rather than dramatic overfilling.
Common Concerns
Typical Treatment Areas
Your BeauLife doctor will assess your facial proportions, lip anatomy and skin quality to recommend the most suitable filler, dosage and injection plan for you.
Restylane Kysse is specifically designed for the lips and perioral area. Using XpresHAn™ technology, it creates a soft, elastic gel that integrates with the lip tissue and moves naturally with expressions, helping avoid a stiff or “duck lip” appearance while still providing noticeable volume and definition.
The main ingredient is stabilised hyaluronic acid (HA), a substance found naturally in the body that helps maintain moisture and elasticity in the skin. The formulation is crosslinked to last longer than naturally occurring HA and includes lidocaine to improve comfort during injections.
You will see fuller, more defined lips immediately after treatment. Mild swelling is normal and typically subsides within a few days as the final shape settles. Clinical studies show that Restylane Kysse can provide improvement for up to 1 year in many patients.
Most patients can return to daily activities shortly after treatment. Temporary side effects such as swelling, redness, tenderness or bruising around the injection sites may occur and usually resolve within a few days. Your doctor will provide specific aftercare advice, such as avoiding strenuous exercise, heat and excessive sun for the first 24 hours.
Restylane Kysse is an FDA-approved HA filler with established safety data when used as directed by trained medical professionals. However, like all injectables, it carries potential risks, including bruising, swelling, infection, lumps or, rarely, more serious complications. A detailed consultation and proper injection technique are essential to minimise these risks.
You may be a good candidate if you:
Restylane Kysse may not be suitable if you are pregnant or breastfeeding, have severe allergies, active skin infections, bleeding disorders, or a history of significant reactions to HA fillers. Your BeauLife doctor will assess your medical history and treatment goals before recommending any procedure.





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